Bubbles and Droplets in Biomedical Applications
When harnessed correctly, the interesting mechanical and chemical effects associated with strong bubble oscillations and collapse, as well as with phase-change events, can be beneficial in numerous applications in biomedicine. These include imaging (e.g., medical ultrasound) and therapy (e.g., drug delivery) using ultrasound or shock waves. We study the dynamics associated with:
- Encapsulated micro-bubbles and micro-droplets
- Payload release of bubble-encapsulated droplets
- Bubble interactions with vessels and soft tissues
- Bubble clouds in lithotripsy using shock waves and high-intensity focused ultrasound
Artistic rendering of microbubble-mediated sonoporation (Cattaneo et al., Nature Physics, 2025).
Controlled tough bioadhesion mediated by ultrasound (Ma et al., Science, 2022).
Schematic overview highlighting the role of ultrasound-responsive agents and their pathway throughout the drug delivery process (Shakya et al., Advanced Drug Delivery Reviews, 2024).